Fracture-separation of articular cartilage in the adult knee.

Conditioned medium derived from mesenchymal Stem cells regenerates’ defected articular cartilage

Background & Aims: One of cell- based technical issues associated with cartilage repair assay is delivering cells to the site of the parts where damage is created. Mesenchymal stem cells (MSCs) with their chondrogenic potential are ideal candidates for cartilage regeneration. High expression of cartilage hypertrophy markers by MSCs would result in apoptosis and ossification. This investigation ...

Experimental Study on Protective Role of NSAID on Articular Cartilage Destruction in Septic Arthritis

Background: Surgical drainage and antibiotic therapy are the cornerstones of treatment protocols in septic arthritis; however, in some circumstances, the diagnosis and initiation of treatment may be retarded by slow disease progression or the time when the patient’s condition precludes early surgery. Therefore, it is beneficial to find ways to reduce the amount of articular injury. This study a...

The comparison of the effect of an aerobic training period and ozone therapy on gene expression of Beclin-1, AMPK and mTOR of articular cartilage tissue in rats model of osteoarthritis

Introduction The aim of the research was to investigate the effect of 8 weeks’ exercise training and ozone therapy on articular cartilage tissue mRNA Beclin-1, AMPK, and mTOR gene expression in rat’s model of osteoarthritis (OA). Materials and Methods In this experimental study, 40 adult male rats 210±10 gr were randomly divided into 5 groups: 1) control (CN), 2) OA, 3) OA + ozone, 4) OA + ex...

TOTAL KNEE ARTHROPLASTY IN PATIENT WITH TIBIAL EXTRA ARTICULAR STRESS FRACTURE

Save the Meniscus, A Good Strategy to Preserve the Knee

With increasing life expectancy, the demand for preservation of native articular cartilage is increasing to delay joint arthroplasties. In the knee, there are many different strategies to preserve the articular cartilage including but not limited to corrective osteotomies, chondral injury restoration, intraarticular injection of cells or growth factors(PRP). However, One of the most important s...